【摘要】 目的 探討2型糖尿?。╰ype 2 diabetic mellitus,T2DM)患者尿蛋白排泄率(urinary albamin excretion rate,UAER)與頸股動脈脈搏波傳導(dǎo)速度(carotid-femoral pulse wave velocity,CF-PWV)的關(guān)系。 方法 2007年1月—2010年11月,將112例T2DM患者按UAER分為兩組,A組(UAER lt;20 μg/min)及B組(UAER gt;20 μg/min)各56例,分別測CF-PWV。 結(jié)果 兩組CF-PWV分別為(11.72±3.67)、(14.25±4.23) m/s,差異有統(tǒng)計學(xué)意義(t=3.381,P=0.001)。 結(jié)論 T2DM患者中,UAER增高者CF-PWV明顯增高,提示動脈粥樣硬化程度與糖尿病腎病的嚴重程度相關(guān)。
引用本文: 張秉濤. 糖尿病患者尿蛋白排泄率與脈搏波傳導(dǎo)速度的關(guān)系. 華西醫(yī)學(xué), 2011, 26(6): 848-849. doi: 復(fù)制
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- 1. 張逸, 張木坤, 劉露, 等. 尿微量白蛋白和糖化血紅蛋白的檢測對糖尿病腎病的臨床意義[J]. 右江民族醫(yī)學(xué)院學(xué)報, 2009, 31(1): 76-77.
- 2. 崔星蕾, 孫長海. 糖尿病腎病69例療效分析[J]. 中國現(xiàn)代醫(yī)生, 2009, 47(22): 58-56.
- 3. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications: report of WHO consultation[R]. Geneva: WHO, 1999.
- 4. 廖二元, 超楚生. 內(nèi)分泌學(xué)[M]. 北京: 人民衛(wèi)生出版社, 2004: 1544-1556.
- 5. Naidu MU, Reddy BM, Yashmaina S, et al. Validity and reproducibility of arterial pulse wave velocity measurement using new device with oscillometric technique: a pilot study[J]. Biomed Eng Online, 2005, 4(3): 49.
- 6. Tanaka H, Munakata M, Kawano Y, et al. Comparison between carotid-fem oral and brachial-ankle pulse wave velocity as measures of arterial stiffness[J]. J Hypertens, 2009, 27(10): 1-6.
- 7. Adler AI, Stevens RJ, Manley SE, et al. Development and progression of nephropathy in type 2 diabetes, the United Kingdom Prospective Diabetes Study (UKPDS 64)[J]. Kidney Int, 2003, 63 (1): 225-232.
- 8. Kohara K, Tabara Y, Tachibana R, et al. Microalbuminuria and arterial stiffness in a general population: the Shimanami Health Promoting Program (J-SHIPP) study[J]. Hypertens Res, 2004, 27(7): 471-477.
- 9. 王曉玉, 劉永銘, 周新人, 等. 2型糖尿病患者脈搏波速度的變化及其影響因素[J]. 中國糖尿病雜志, 2010, 18(10): 767-769.
- 10. Furtner M, Kiechl S, Mair A, et al. Urinary albumin excretion is independently associated with carotid and femoral artery atherosclerosis in the general population[J]. Eur Heart J, 2005, 26(3): 279-287.
- 11. 張春香, 李穎. 2型糖尿病患者尿微量白蛋白與肌酐比值臨床相關(guān)因素分析[J]. 中國現(xiàn)代醫(yī)生, 2009, 47(4): 10-11.
- 12. 悉齊紅. 2型糖尿病患者MAU和頸動脈粥樣硬化的研究[J]. 實用糖尿病雜志, 2009, 5(2): 15-16.