• 四川大學(xué)華西醫(yī)院普外科（成都610041）;

目的探討原發(fā)性膽囊癌治療的措施。方法對(duì)我院1998年4月至2003年2月外科治療的122例原發(fā)性膽囊癌患者的臨床資料，結(jié)合部分患者隨訪結(jié)果進(jìn)行分析總結(jié)。結(jié)果19例Ⅰ、Ⅱ及Ⅲ期膽囊癌患者手術(shù)治療效果滿意； 103例Ⅳ、Ⅴ期膽囊癌患者中34例行根治或擴(kuò)大根治術(shù)，根治切除率為33.0%，余69例行姑息性手術(shù)治療，行膽囊癌根治術(shù)后患者的平均生存時(shí)間明顯長(zhǎng)于姑息性手術(shù)者（17.6個(gè)月 vs 7.3個(gè)月）。結(jié)論對(duì)膽囊癌應(yīng)采取積極的、個(gè)體化的治療措施。擴(kuò)大根治術(shù)可使部分Ⅳ、Ⅴ期膽囊癌患者受益。應(yīng)注意淋巴結(jié)清掃的范圍和做到無殘留癌的根治性切除。對(duì)綜合治療的研究還需進(jìn)一步深入。

引用本文： 楊培,嚴(yán)律南,智星,李波. 122例原發(fā)性膽囊癌外科治療體會(huì). 中國(guó)普外基礎(chǔ)與臨床雜志, 2004, 11(3): 253-254. doi: 復(fù)制

版權(quán)信息： ?四川大學(xué)華西醫(yī)院華西期刊社《中國(guó)普外基礎(chǔ)與臨床雜志》版權(quán)所有，未經(jīng)授權(quán)不得轉(zhuǎn)載、改編

1. Muratore A, Polastri R, Capussotti L. Radical surgery for gallbladder cancer: current options [Ｊ]. Eur J Surg Oncol, 2000; 26(5)∶438.
2. Suzuki K, Kimura T, Ogawa H. Is laparoscopic cholecystectomy hazardous for gallbladder cancer? [Ｊ]. Surgery, 1998; 123(3)∶311.
3. Z’graggen K, Birrer S, Maurer CA, et al. Incidence of port site recurrence after laparoscopic cholecystectomy for preoperatively unsuspected gallbladder carcinoma [Ｊ]. Surgery, 1998; 124(5)∶831.
4. Varshney S, Buttirini G, Gupta R. Incidental carcinoma of the gallbladder [Ｊ]. Eur J Surg Oncol, 2002; 28(1)∶4.
5. Shimada H, Endo I, Togo S, et al. The role of lymph node dissection in the treatment of gallbladder carcinoma [Ｊ]. Cancer, 1997; 79(5)∶892.
6. Kondo S, Nimura Y, Hayakawa N, et al. Regional and paraaortic lymphadenectomy in radical surgery for advanced gallbladder carcinoma [Ｊ]. Br J Surg, 2000; 87(4)∶418.
7. Oohashi Y, Shirai Y, Wakai T, et al. Adenosquamous carcinoma of the gallbladder warrants resection only if curative resection is feasible [Ｊ]. Cancer, 2002; 94(11)∶3000.
8. Kresl JJ, Schild SE, Henning GT, et al. Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma [Ｊ]. Int J Radiat Oncol Biol Phys, 2002; 52(1)∶167.
9. 杜繼東， 李為民， 許紅兵， 等. 經(jīng)肝動(dòng)脈插管化療栓塞術(shù)治療晚期膽囊癌肝轉(zhuǎn)移32例 [Ｊ]. 世界華人消化雜志， 2000； 8（1）∶117.
  1. 1. Muratore A, Polastri R, Capussotti L. Radical surgery for gallbladder cancer: current options [Ｊ]. Eur J Surg Oncol, 2000; 26(5)∶438.
  2. 2. Suzuki K, Kimura T, Ogawa H. Is laparoscopic cholecystectomy hazardous for gallbladder cancer? [Ｊ]. Surgery, 1998; 123(3)∶311.
  3. 3. Z’graggen K, Birrer S, Maurer CA, et al. Incidence of port site recurrence after laparoscopic cholecystectomy for preoperatively unsuspected gallbladder carcinoma [Ｊ]. Surgery, 1998; 124(5)∶831.
  4. 4. Varshney S, Buttirini G, Gupta R. Incidental carcinoma of the gallbladder [Ｊ]. Eur J Surg Oncol, 2002; 28(1)∶4.
  5. 5. Shimada H, Endo I, Togo S, et al. The role of lymph node dissection in the treatment of gallbladder carcinoma [Ｊ]. Cancer, 1997; 79(5)∶892.
  6. 6. Kondo S, Nimura Y, Hayakawa N, et al. Regional and paraaortic lymphadenectomy in radical surgery for advanced gallbladder carcinoma [Ｊ]. Br J Surg, 2000; 87(4)∶418.
  7. 7. Oohashi Y, Shirai Y, Wakai T, et al. Adenosquamous carcinoma of the gallbladder warrants resection only if curative resection is feasible [Ｊ]. Cancer, 2002; 94(11)∶3000.
  8. 8. Kresl JJ, Schild SE, Henning GT, et al. Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma [Ｊ]. Int J Radiat Oncol Biol Phys, 2002; 52(1)∶167.
  9. 9. 杜繼東， 李為民， 許紅兵， 等. 經(jīng)肝動(dòng)脈插管化療栓塞術(shù)治療晚期膽囊癌肝轉(zhuǎn)移32例 [Ｊ]. 世界華人消化雜志， 2000； 8（1）∶117.